Biomega is a dark science fiction manga written and illustrated by Tsutomu Nihei. The story is set in a bleak post apocalyptic future where humanity is on the brink of extinction due to the spread of a mysterious infection known as the N5S virus, which transforms humans into zombie like drone creatures. The manga follows Zoichi Kanoe, a near-immortal agent working for Toa Heavy Industries, who travels across vast megastructures, ruined cities, and alien environments in search of humans who can resist the infection and hold the key to humanity’s survival. Accompanied by his AI partner Fuyu, integrated into his advanced motorcycle system, Zoichi battles powerful enemies, bio mechanical creatures, and secret organizations while uncovering the truth behind the virus and the fate of humanity. Biomega manga is known for its cyberpunk atmosphere, minimal dialogue, dark sci fi themes, post apocalyptic worldbuilding, and philosophical storytelling, making it one of Tsutomu Nihei’s most visually striking and atmospheric works, often compared to BLAME!, Akira, and Ghost in the Shell.

Alternative Titles:
Biomega
Violent Infectious Disease Covers All the World… The Omega
バイオメガ
Baio Mega